HOPX antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: HOP homeobox
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 8-12 kDa
Uniprot: Q9BPY8
Gene id: 84525
Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Field of research: Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, WB
Dilution: WB: 1:500-1:2000; IF: 1:50-1:200
Target: HOPX
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: HOP homeobox
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 8-12 kDa
Uniprot: Q9BPY8
Gene id: 84525
Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Field of research: Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IF, WB
Dilution: WB: 1:500-1:2000; IF: 1:50-1:200
Target: HOPX
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat