ACP3 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 8D6
Isotype: IgG2a
Immunogen: acid phosphatase, prostate
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 48 kDa
Uniprot: P15309
Gene id: 55
Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Target: ACP3
Purification: Protein A+G purification
Reactivity: Human, rat
Clonality: Monoclonal
Clone: 8D6
Isotype: IgG2a
Immunogen: acid phosphatase, prostate
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 48 kDa
Uniprot: P15309
Gene id: 55
Background: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions(pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion(DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling.
Field of research: Cancer, Immunology, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Target: ACP3
Purification: Protein A+G purification
Reactivity: Human, rat